Sugarcoating Seizures – a Sweet Deal?

Statin-induced diabetes: too sweet a deal?

Bottom line Statins modestly increase blood glucose levels, which leads to 1 in 250 or so patients crossing the “diabetic threshold” in a 5-year period. Pre-existing elevated blood glucose levels, other diabetes risk factors, or higher statin doses might slightly increase the risk. This should not change statin prescribing, as statins reduce cardiovascular events and allcause mortality in appro...

Chocolate and cardiovascular disease: a sweet deal?

‘Take two of these chocolates daily, and call me in a month.’ Who among us would not want to be able to provide such a delicious prescription to our patients who carry the complicated and eventually fatal diagnosis of heart failure? Unfortunately, the solution is not that simple, yet the recent study by Flammer et al. may bring us a step closer to understanding the relationship between cocoa, e...

Sugarcoating ER Stress

The hexosamine biosynthetic pathway (HBP) generates metabolites for protein N- and O-glycosylation. Wang et al. and Denzel et al. report a hitherto unknown link between the HBP and stress in the endoplasmic reticulum. These studies establish the HBP as a critical component of the cellular machinery of protein homeostasis.

Big Deal - good deal? Or is there a better deal?

A raw deal.

Rafina Khateeb, MD, Tejal Gandhi, MD, Gurpreet Dhaliwal, MD Division of General Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan; Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan; Medical Service, San Francisco Veterans Affairs Medical Center, University of California S...